Trabalhos
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Leishmaniose
> An Overview of Immunotherapeutic Approaches Against Canine Visceral Leishmaniasis: What Has Been Tested on Dogs and a New Perspective on Improving Treatment Efficacy.
Gonçalves AAM, Leite JC, Resende LA, Mariano RMDS, Silveira P, Melo-Júnior OAO, Ribeiro HS, de Oliveira DS, Soares DF, Santos TAP, Marques AF, Galdino AS, Martins-Filho OA, Dutra WO, da Silveira-Lemos D, Giunchetti RC.
Front Cell Infect Microbiol. 2019 Dec 18;9:427. doi: 10.3389/fcimb.2019.00427. eCollection 2019.
> Canine visceral leishmaniasis biomarkers and their employment in vaccines.
Giunchetti RC, Silveira P, Resende LA, Leite JC, Melo-Júnior OAO, Rodrigues-Alves ML, Costa LM, Lair DF, Chaves VR, Soares IDS, de Mendonça LZ, Lanna MF, Ribeiro HS, Maia-Gonçalves AA, Santos TAP, Roatt BM, Aguiar-Soares RDO, Vitoriano-Souza J, das Dores Moreira N, Mathias FAS, Cardoso JMO, Coura-Vital W, Galdino AS, Viana KF, Martins-Filho OA, Silveira-Lemos DD, Dutra WO, Reis AB. Vet Parasitol. 2019 Jul;271:87-97. doi: 10.1016/j.vetpar.2019.05.006. Epub 2019 May 20.
> In Situ Cellular Response Underlying Successful Treatment of Mucosal Leishmaniasis with a Combination of Pentavalent Antimonial and Pentoxifylline.
Faria DR, Barbieri LC, Koh CC, Machado PRL, Barreto CC, Lima CMF, Lessa MM, Carvalho E, Gollob KJ, Dutra WO. Am J Trop Med Hyg. 2019 Aug;101(2):392-401. doi: 10.4269/ajtmh.19-0139.
> Leishmania infantum induces expression of the negative regulatory checkpoint, CTLA-4, by human naive CD8+ T cells.
Viana AG, Magalhães LMD, Giunchetti RC, Dutra WO, Gollob KJ.
Parasite Immunol. 2019 Sep;41(9):e12659. doi: 10.1111/pim.12659. Epub 2019 Jul 1.
Doença de Chagas
> Diet Alters Serum Metabolomic Profiling in the Mouse Model of Chronic Chagas Cardiomyopathy.
Lizardo K, Ayyappan JP, Ganapathi U, Dutra WO, Qiu Y, Weiss LM, Nagajyothi JF. Dis Markers. 2019 Dec 20;2019:4956016. doi: 10.1155/2019/4956016. eCollection 2019.
> MMP-2 and MMP-9 plasma levels are potential biomarkers for indeterminate and cardiac clinical forms progression in chronic Chagas disease.
Medeiros NI, Gomes JAS, Fiuza JA, Sousa GR, Almeida EF, Novaes RO, Rocha VLS, Chaves AT, Dutra WO, Rocha MOC, Correa-Oliveira R. Sci Rep. 2019 Oct 2;9(1):14170. doi: 10.1038/s41598-019-50791-z.
> Co-infection with distinct Trypanosoma cruzi strains induces an activated immune response in human monocytes.
Magalhães LMD, Passos LSA, Chiari E, Galvão LMC, Koh CC, Rodrigues-Alves ML, Giunchetti RC, Gollob K, Dutra WO. Parasite Immunol. 2019 Nov;41(11):e12668. doi: 10.1111/pim.12668. Epub 2019 Sep 30
> Evidence of Different IL-1β Activation Pathways in Innate Immune Cells From Indeterminate and Cardiac Patients With Chronic Chagas Disease.
Medeiros NI, Pinto BF, Elói-Santos SM, Teixeira-Carvalho A, Magalhães LMD, Dutra WO, Correa-Oliveira R, Gomes JAS. Front Immunol. 2019 Apr 18;10:800. doi: 10.3389/fimmu.2019.00800. eCollection 2019.
> PD1 and PDL1 molecules control suppressor activity of regulatory T cells in chronic Chagas cardiomyopathy patients.
Damasio MPS, Rocha MOC, Sousa GR, Ferreira KS, Fares-Gusmão RCG, Medeiros NI, Araujo FF, Chaves AT, Dutra WO, Correa-Oliveira R, Gomes JAS. Hum Immunol. 2019 Jul;80(7):517-522. doi: 10.1016/j.humimm.2019.03.009. Epub 2019 Mar 7.
> Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease.
Passos LSA, Magalhães LMD, Soares RP, Marques AF, Alves MLR, Giunchetti RC, Nunes MDCP, Gollob KJ, Dutra WO. Front Immunol. 2019 Jan 4;9:3015. doi: 10.3389/fimmu.2018.03015. eCollection 2018.
Obesidade
> An overview about DNA methylation in childhood obesity: Characteristics of the studies and main findings.
Lima RS, de Assis Silva Gomes J, Moreira PR.
J Cell Biochem. 2020 Jun;121(5-6):3042-3057. doi: 10.1002/jcb.29544. Epub 2019 Nov 10. PMID: 31709602
Medeiros NI, Mattos RT, Menezes CA, Fares RCG, Talvani A, Dutra WO, Rios-Santos F, Correa-Oliveira R, Gomes JAS.Eur J Nutr. 2018 Oct;57(7):2421-2430. doi: 10.1007/s00394-017-1515-y. Epub 2017 Jul 22.PMID: 28735358
Oliveira AAB, Melo NFM, Vieira ÉDS, Nogueira PAS, Coope A, Velloso LA, Dezonne RS, Ueira-Vieira C, Botelho FV, Gomes JAS, Zanon RG.Neurochem Int. 2018 Nov;120:140-148. doi: 10.1016/j.neuint.2018.08.010. Epub 2018 Aug 20.PMID: 30138641
> Swimming reduces fatty acids-associated hypothalamic damage in mice.
Nogueira PAS, Pereira MP, Soares JJG, de Assis Silva Gomes J, Ribeiro DL, Razolli DS, Velloso LA, Neto MB, Zanon RG.J Chem Neuroanat. 2020 Jan;103:101713. doi: 10.1016/j.jchemneu.2019.101713. Epub 2019 Nov 11.PMID: 31726089
Mattos RT, Medeiros NI, Menezes CA, Fares RC, Franco EP, Dutra WO, Rios-Santos F, Correa-Oliveira R, Gomes JA.PLoS One. 2016 Dec 15;11(12):e0168610. doi: 10.1371/journal.pone.0168610. eCollection 2016.PMID: 2797779
Ribeiro SMTL, Lopes LR, Paula Costa G, Figueiredo VP, Shrestha D, Batista AP, Nicolato RLC, Oliveira FLP, Gomes JAS, Talvani A.Immun Ageing. 2017 Mar 11;14:6. doi: 10.1186/s12979-017-0089-0. eCollection 2017.PMID: 28293269
Doença Periodontal
> Effect of porous tantalum on the biological response of human peripheral mononuclear cells exposed to Porphyromonas gingivalis.
Temponi EF, Souza PEA, Souto GR, Magalhães LMD, Dutra WO, Gollob KJ, Silva TA, Soares RV. J Investig Clin Dent. 2019 Nov;10(4):e12472. doi: 10.1111/jicd.12472. Epub 2019 Sep 27.
> Composite-derived monomers affect cell viability and cytokine expression in human leukocytes stimulated with Porphyromonas gingivalis.
Neves SO, Magalhães LMD, Corrêa JD, Dutra WO, Gollob KJ, Silva TA, Horta MCR, Souza PEA. J Appl Oral Sci. 2019 Jun 3;27:e20180529. doi: 10.1590/1678-7757-2018-0529.
> J Periodontal Res. 2020 Jun;55(3):426-431. doi: 10.1111/jre.12726. Epub 2020 Jan 14.
DNA methylation profile of genes related to immune response in generalized periodontitis
Andrea Mara Azevedo, Luiz Paulo Carvalho Rocha , Simone Angélica de Faria Amormino , Carolina Cavalieri Gomes , Walderez Ornelas Dutra , Ricardo Santiago Gomez , José Eustáquio da Costa , Paula Rocha Moreira
COSTA, G. M. F. ; ROCHA, L. P. C. ; SIQUEIRA, S. R. D. T. ; MOREIRA, P. R. ; ALMEIDA-LEITE, C. M. .
> NO ASSOCIATION OF POLYMORPHISMS IN NAV1.7 OR NERVE GROWTH FACTOR RECEPTOR GENES WITH TRIGEMINAL NEURALGIA. PAIN MEDICINE, v. 19, p. 1-8, 2018